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Retatrutide: GI adverse events dose-dependent

While there are many reasons why someone could feel fatigued, B12 is a part of the picture and correcting the deficiency can greatly improve energy levels

doi:10.1097/ICO.0b013e3181d836f3 5

Interestingly, mitochondrial rescue ameliorates this phenotype, lending credence to the idea that there is an intersection between mitochondrial dysfunction, lipid metabolism, and the progression of AMD [142]